U principu, lečenje ne bi smelo da traje duže od 8-12 nedelja, uključujući i period of time postepene obustave leka. Terapija se ne sme produžavati bez prethodne reevaluacije stanja pacijenta.

Benzodiazepini nisu indikovani kod pacijenata sa teškim oštećenjem funkcije jetre, s obzirom na to da mogu da izazovu nastanak encefalopatije. Kod pacijenata sa hroničnim oboljenjem jetre, može biti neophodno smanjiti dozu leka.

Fenobarbital uzet istovremeno može dovesti do aditivnog efekta na CNS. Povećan je rizik od sedacije i respiratorne depresije. Poznato je da fenobarbital indukuje CYP3A4 enzim i ubrzava metabolizam diazepama u jetri, što smanjuje efikasnost diazepama.

Kod oštećene funkcije bubrega ne dolazi do klinički značajne promene u poluvremenu eliminacije diazepama, tako da obično nije neophodno prilagođavanje doze.

Istovremena primena leka Bensedin, rastvor za injekciju/infuziju i opioida (lekovi za ublažavanje jakih bolova, lekovi koji se primenjuju kao supstituciona terapija i određeni lekovi protiv kašlja) povećava rizik od pospanosti, poteškoća sa disanjem (respiratorna depresija), kome i može biti opasna po život. Zbog ovoga istovremenu primenu treba razmotriti samo kada druge terapijske opcije nisu moguće.

Never get Co-codamol thirty/five hundred Tablets If you're pregnant or think you will be pregnant unless you may have talked over this with the prescriber and the main advantages of remedy are considered to outweigh the probable harm more info for the baby.

o you have got taken it in accordance with the Directions provided with the prescriber or in the knowledge furnished While using the drugs and

Will not retain out-of-day or unwelcome medicines. Get them to your local pharmacy that will get rid of them in your case.

If any of the aspect effects turn into significant, or in the event you detect any side result not stated On this leaflet, you should explain to your physician or pharmacist.

– you have taken it according to the Guidance presented from the prescriber or in the data offered with the medication and

Benzodiazepines can pose a risk without having you at any time recognizing it. Using safety measures is the most effective methods to safeguard on your own from unknowingly getting these medication.

Co-codamol 30/five hundred Tablets might lead to dizziness or drowsiness and you should not drive or operate machinery Should you be affected this way. Codeine may well disturb your eyesight.

Codeine really should not be employed for suffering reduction in little ones and adolescents following elimination of their tonsils or adenoids on account of Obstructive read more Rest Apnoea Syndrome (sleep disruption because of respiratory pauses). They might be at improved danger of critical aspect effects in case of morphine toxicity.

Read through all of this leaflet cautiously Before you begin using this medicine because it incorporates essential info for you personally.